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Cerebral haemorrhage.subarachnoid haemorrhage.stroke and other cerebrovascular events have been reported in patients treated with 5-HT 1 agonists. and some have resulted in fatalities. In a number of cases.it appears possible that the cerebrovascular events were primary.the agonist having been administered in the incorrect belief that the symptoms experienced were a consequence of migraine.when they were not. It should be noted that patients with migraine may be at increased risk of certain cerebrovascular events (e.g. stroke.haemorrhage.transient ischaemic attack).

Cases of life-threatening serotonin syndrome have been reported during combined use of selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs) and triptans. There have been reports describing patients with symptoms compatible with serotonin syndrome (including altered mental status.autonomic instability and neuromuscular abnormalities) following the use of SSRIs or serotonin norepinephrine reuptake inhibitors (SNRIs) and triptans.

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A serious side effect due to Rizatriptan (Maxalt.Rizact) usage is rare. However.few people may experience some serious side effects like blue colored nails.coldness in hand or feet.hearing changes.seizures.or mood changes. This medication may increase the level of serotonin in the body and rarely cause a serious condition called serotonin syndrome rizact buy toxicity. The risk of this happening increases if you take other drugs that increase serotonin. Call your doctor right away if you get any serious side effect due to this medication. Some of the common side effects of Rizatriptan are flushing.tingling sensation.numbness.prickling.warm feeling.chest/jaw/neck tightness.weakness.drowsiness.or giddiness. If any of these conditions persist rizact buy deteriorate.get immediate medical attention. The side effects that are listed above are not a complete set of side effects due to Rizatriptan. You may experience some other side effects.

Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. Because there is a theoretical basis that these effects may be additive.use of ergotamine-containing or ergot-type medications (like dihydroergotamine or methysergide) and rizatriptan within 24 hours is contraindicated. Due to an additive effect.the concomitant use of rizatriptan and ergotamine/ergot derivatives (including methysergide) increases the risk of coronary artery vasoconstriction and hypertensive effects. This combination is contraindicated.

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